الصيدلانية وسيطة بنزوكاين كاس 94-09-7

Benzocaine  

Chemical Data

CAS No

94-09-7

Molecular Formula

C₉H₁₁NO

Molecula Weight

166.1965

EINECS NO

202-303-5

Appearance

White or almost white crystalline powder or colorless crystals

Solubility:Very slightly soluble in water,freely soluble in ethanol(96%)

Packing

25kg fibre drum

Uses

Pharmaceutical intermediates and cosmetic

Storage

Keep in sealed and damp proof place.

Chemical Specification

Identification

Infrared absorption spectrum therewith corresponding spectrum

Melting point

89-92°C

Appearance of solution

The solution is clear and colorless

Acidity or alkalinity

1.     The solution remain colorless

2.     ≦0.5ml of 0.01M solution hydroxide is required to change the color of the indicator

Content (dry substance)

99-101% min

Loss on drying

0.5% max

Sulphated ash

0.1% max

Pb

1ppm max

Heavy metals

0.001% max

Related substance

Any unspecified impurity ≦0.1%

Total impurities ≦0.5%

Granularity

Not less than 90% of particles pass 20 mesh

Not more than 90% of particles pass 40 mesh

Total numbers of colony

No more than 80cfu/g

Yeasts and molds

No more than 80cfu/g

Live mites and mite eggs(CP)

E.Coli (CP)

 No live mite and mite eggs are detected

Negative

Staphylococcus aureus(CP)

Negative

Pseudomonas aeruginosa (CP)

Negative

Conclusion

Conform to EP8